What Is Stargardt Disease

Learn more about Stargardt Disease, including The Symptoms, The Causes, and The Treatments.

What Is Stargardt Disease

Stargardt disease is also referred to as juvenile macular degeneration, juvenile macular dystrophy or stargardt macular dystrophy. It is an inherited condition that can appear in childhood or adolescence, Stargardt disease affects the macula, your central vision, where you see colour and fine detail. The photoreceptors (light sensitive receptors) in the macula become permanently damaged, causing the loss of your central vision. Your ability to see colour, fine detail, recognise faces, read and see clearly, becomes severely impaired. Patients with Stargardt disease usually have normal peripheral vision.

Stargardt Disease - Symptoms

• Unclear blurry vision

• Straight edges appear wavy or distorted

• Distorted vision

• Difficulty in reading

• Difficulty in recognising faces

• Poor colour vision

• Blank or patchy central vision

• Use begin to turn your head to see better

Stargardt Disease - Causes

• Stargardt disease is inherited and caused by faulty genes.

• In Stargardt disease, the faulty gene causes a buildup waste product called lipofuscin (they appear as yellow flecks) to accumulate around the macula, which damages the photoreceptors; this leads to the loss of your central vision.

• As the disease progresses, an oval lesion (bull’s eye configuration) can be seen on the macula.

• If Stargardt disease is caused by a mutation in the ELOVL4 gene, it is inherited in an autosomal dominant pattern. This means one of your parents has passed the disease onto you and usually they will also have stargardt disease.

• Most cases of the stargardt disease are caused by a mutation in the ABCA4 gene; it is inherited as a recessive condition. This is where both parents are carriers of the faulty gene and pass it on to their child, the child then gets stargardt disease. Carriers of the recessive gene usually do not suffer from stargardt disease.

Stargardt Disease - Treatments

There is sadly no treatment for stargardt disease, however there is ongoing research in gene therapy and stem cells.

• Research has shown that exposure to UV light in the eyes may increase further retina & macula damage. Wearing wrap around sunglasses will help protect your eyes from UV light and blue light.  Sunglasses should have 100% UV protection and polarised lenses in your sunglasses will also help protect your eyes from glare.

• You may be referred to a low vision clinic if your sight is significantly affected, a low vision clinic will give you practical advice and magnifying aids to help you see better

• Some hospital eye services have an ECLO (Eye Clinic Liaison Officer) who can provide further support

• Check with your ophthalmologist if you can be registered as sight impaired or severely sight impaired. Registration can help with financial concessions and expert practical help

• Contacting the RNIB or macular society for further support, visual aids and practical advice

• Gene therapy research is looking into injecting the ‘normal’ gene into the diseased retinal cells, to replace the faulty gene and stop any further progression of vision loss.

• Stem cell research is looking into developing stem cells that can replicate and replace damaged retinal cells in stargardt disease.

• Research is also taking place with medication that can reduce the amount of vitamin A produced by the retinal cells affected by stargardt disease. Patients with stargardt disease are unable to remove vitamin A from the macula.

Children will need to be reviewed by different governing bodies, which will produce a statement on how to best help the child learning & development. Please click the link for further information.


RNIB, 0303 123 9999, helpline@rnib.org.uk, or visit the RNIB at 105 Judd St, London WC1H 9NE

Macular Society: PO Box 1870, Andover, SP10 9AD. Tel: 0300 3030 111  Web: www.macularsociety.org

Bhavita Magudia
Stargardt Disease - Explained
February 21, 2019

The information below is not intended for self diagnose of an eye condition. If you are worried or suffering from an eye problem, please call us on 0208 524 2887 and book in to see us.

Our Customer Testimonials
Marilyn Rood
Testimonial 5 stars
November 2020

For premium eye examination and up to date technical equipment and knowledge look no further than Ideal Vision.

Phyllis Lundy
Testimonial 5 stars
November 2020

The whole family and relatives have been customers of Eyedeal Vision Opticians for many years and we have always had a very professional service. We are always treated with much respect and would highly recommend the practice.

Lisa Marie Sherwood-Ball
Testimonial 5 stars
November 2020

Amazing team. Very professional and elite. These aren’t your ordinary ‘spec savers’ company. A family run business who care ❤️

Fiona Everall
Testimonial 5 stars
November 2020

Been going to Eyedeal for 8 years. Always so helpful and a very nice staff. Always friendly what more could you ask!

Carol Warwick
Testimonials 5 stars
November 2020

Always friendly and ultra professional even in these difficult times. Would thoroughly recommend them.

Amanda Oneill
Testimonials 5 stars
November 2020

I have been going to Eyedeal Vision for years as I used to deliver there post when I worked at Royal Mail Chingford I have moved offices 3 years ago I still go to them as they are so friendly and polite and very patient as I also that my niece and nephew who is Autism and non verbal he uses his iPad to communicate which they so great patience with him he is a very clever boy. Just been for our yearly check lucky for the children there eyes are perfect mine getting worse I was bit worried about my new glasses they soon put me at ease they really are the best opticians I have ever been I really do recommend them Amanda Oneill

Elaine Watts‎
Testimonials 5 stars
October 2020

Our whole family visit Eyedeal Vision from young to not so young. Service is second to none from everyone, they make you feel that you are their only customer and every need is met, with a smile and efficiency. During these difficult times it is the one place that we go to with complete confidence. Keep up the good work.

Andy Bastick
Testimonials 5 stars
October 2020

A fantastic local opticians friendly polite and very professional Pop in and enjoy the experience.

Alex Vanderlip
Testimonials 5 stars
November 2020

Service here was superb - they managed to turn around an order for varifocal sunglasses in a week, which was mightily impressive. Lovely team and always service with a smile.

Brian Thorogood
Testimonials 5 stars
September 2020

I have been getting my glasses from Eyedeal Vision since the 1980’s and always been treated with the most kindest attention, my glasses have always suited me And I will never go anywhere else the staff are very expert in what they do.

View Our Customer Testimonials
Contact Us

Please Contact Eyedeal Vision Opticians at Chingford for any queries you may have. If you would like to book an appointment for an eye examination, please select the Book Your Appointment link. For any other enquiry please use the Contact Us form here.

Contact Us Form
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Eyedeal Vision Opticians

If you would like to request an appointment for one of our eye examination, please select the Request Your Appointment link Above.